Vaccine is a biological product that initiates
stimulation to antibodies and helps provide immunity against
infectious and chronic diseases. There are various types of vaccines
such as inactivated vaccines, subunit vaccines, recombinant vector
vaccines and DNA vaccines. Vaccines are mainly prophylactic in nature
along with therapeutic effect. The wide application of vaccines is
expected to favor the therapeutic vaccines market. Therapeutic
vaccine is a combination of biologics that is designed to develop
immunity against the abnormal cells in the body. Therapeutic vaccines
can be modified as per application and can be used to treat various
disorders and disease such various types of cancer, HIV infectious
diseases, and Alzheimer’s disease. Therapeutic vaccines help treat
a disorder by inducing or providing strength to the immune response.
However, the existence of a handful of established therapeutic
vaccines and their explored property has provided a resistance in the
therapeutic vaccine market growth till now. Although, various studies
and demand for biologics has provided a significant shift of growth
graph towards high value.
Therapeutic vaccines are particularly designed to
treat patients who have tested HIV positive. HIV virus deteriorates
the immune system that results in weakening of its response towards
the disease and abnormality causing agents resulting in inability to
fight with those agents. According to, U.S. Department of Health and
Human Services, in 2010, there were various vaccines under phase 3
clinical trials, such as gp100 melanoma vaccine, Lucanix
(Belagenpumatucel-L) (NovaRx Corp.) for NSCLC, GSK1572932A (GSK) for
melanoma and NSCLC, and Stimuvax (Emepepimut-S) (Merck
KgaA/Oncothyreon).
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Therapeutic Vaccines Market Taxonomy:
By Vaccines Type
-
Auto Immune Diseases Vaccines
-
Neurological Disease Vaccines
-
Cancer Vaccines
-
Infectious Diseases Vaccines
By Indication
-
Cancer
-
Breast Cancer
-
Prostate Cancer
-
Lung cancer
-
Melanoma
-
others
-
Infectious Disease
-
HIV
-
Hepatitis B
-
Hepatitis C
-
Others
-
Other Chronic Diseases
-
Alzheimer’s
-
Allergy
-
Others
Rising demand for biologics and drugs for
specific treatment is expected to favor growth of the therapeutic
vaccines market in the near future
The global therapeutic vaccines market is
significantly affected by increasing prevalence of cancer, HIV
infection, cardiovascular diseases, and various chronic diseases.
This exponential growth in prevalence of such diseases is expected to
increase the demand for biologic drugs for specific or targeted
response, which is further projected to support increase in growth of
therapeutic vaccines industry in the near future. According to AVERT,
a global organization involved in providing information and education
on HIV and AIDS to the general population, in 2016, around 37 million
people worldwide were infected by HIV and 40% were unaware about it.
According to a report by America’s Biopharmaceutical Research
Companies, in 2013, around 300 vaccines were in development, with
research focused on prevention and treatment. These vaccines include
treatment of various health issues and diseases such as allergy,
cancer, infectious disease, and neurological disorder. Furthermore,
according to data from the U.S. Centers for Disease Control and
Prevention (CDC), therapeutic vaccines have led to the eradication of
around 10 infectious diseases by up to 90% in the U.S.
Major players in the therapeutics vaccines market
are engaged in research and development process. For instance,
Dendreon Corporation – a biotechnology company engaged in
development, discovery and commercialization of novel therapeutic
product – launched Provenge, the first FDA-approved immunotherapy
drug for treating prostate cancer.
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Research and development activities by the
major players to favor the therapeutic vaccines market in the near
future:
The global therapeutic vaccines market is
competitive and highly fragmented. Although, the major players in the
market are developing novel products and spending significantly in
research and development to give a competitive edge to their peers.
For instance, due to the strong product pipeline under therapeutic
vaccines segment Merck and GlaxoSmithKline are considered to be the
toughest competitor in the market. Key players operating in the
therapeutic vaccines market include Novartis AG, GlaxoSmithKline,
Pfizer, Cytos Biotechnology AG, Argos Therapeutic Inc., Merck &
Co., Dendreon Corp, Bavarian Nordic A/S, and Agenus, Inc.
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