Protein A Resin Market – Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016–2024

Protein A Resin Market Overview :

Protein A is a bacterial protein, which has capacity to bind mammalian antibodies of class immunoglobulin G with great affinity. Protein G binds to all subclasses of human immunoglobulin G (IgG) makes it useful for purifying polyclonal or monoclonal IgG antibodies whose subclasses have not been determined. Monoclonal antibodies are defined as ‘an antibody produced by a single clone of cells'. It can be used to carry drugs, toxins, or radioactive substances traditional to cancer cells. Monoclonal antibodies have been showing promising results in the management of chronic diseases such as cancers and rheumatoid arthritis. These are essential and are broadly used as purification and separation materials due to high resolution, across the biopharmaceutical industry. Natural protein A can be produced from Staphylococcus aureus, though protein A is now commonly produced recombinant in Escherichia coli. Chromatography with these has several advantages as a separation method, over conventional techniques such as solvent extraction, crystallization, and distillation.

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Increasing diagnostic and therapeutic applications of monoclonal antibodies in management of chronic diseases such as cancer, rheumatoid arthritis beside with increasing R&D activities on monoclonal antibodies will drive protein A resins market over the forecast period. High selectivity and improved antibody production coupled with ease of operation in large and small scale antibody purification and immunoprecipitation will further drive growth of the protein A resins market growth. Encouraging government policies in terms of formulation of suitable policies for startups and administration of funding for development of next-gen medical products are expected to play a vital role in driving growth. Development of cost effective protein A resin is also expected to boost growth of the market.

Protein A Resin Market

On the basis of Product, the protein A resin market is classified into:

• Natural Protein A Resin
• Recombinant Protein A Resin

On the basis of Application, the protein A resin market is classified into:

• Immunoprecipitation
• Antibody Purification

On the basis of Matrix Type, the protein A resins is classified into:

• Glass or Silica
• Agarose and
• Organic Polymer

On the basis of end users, the protein A resins is classified into:

• Biopharmaceutical Manufacturers
• Clinical Research Laboratories and
• Academic Institutions

Geographically, North America accounted for the leading share in the global protein A resin market, due to the large number of clinical trials for the monoclonal antibody based therapeutics and increasing traction for biosimilars with the recent U.S. Food and Drugs Administration (FDA) in the region. The U.S. contributed largest revenue to the North American as well as global protein A resin industry. The country is expected to remain the largest market for protein A resin globally during the forecast period. This market is expected to witness the highest growth in Asia-Pacific during the forecast period, owing to the increasing compliance for biosimilars and shifting global attentiveness for expanding biopharmaceutical manufacturing capacities in the emerging economies of the region.

Increasing awareness about random methods to purify monoclonal antibodies is obstructing the Protein A Resins market. High costs associated with the Protein A resins is also a major factor restraining the market growth. Geographic expansion, agreements, strategic acquisitions, and continuous effort to improve the product assortment are the key strategies adopted by the market players to stand the competitive market.

There is an increasing demand for early detection and prevention of curable diseases especially in the adults. This is going to be a key opportunity in the market as the percentage of adult population is increasing on a daily basis owing to the rise in life expectancy among the global population. The demand for safe and valuable treatments is gaining prevalence in the market. This factor coupled with unmet medical needs among the patients will fuel the growth of the global sickle cell anemia therapeutics market.

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Key players operating in the global protein A resin market are Thermo Fisher Scientific Inc., General Electric Company, Merck KGaA, Repligen Corporation, Tosoh Corporation, Expedeon Ltd., Novasep, and GenScript, among others.

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Organ-on-a-chip Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016-2024

Organ-on-a-chip Market Overview:
Organ-on-a-chip is gaining prominence on the backdrop of regulatory measures on animal testing and growing complexity in therapeutic applications. Various players are trying to capitalize on lucrative growth opportunities in the organ-on-a-chip devices market. It is a unique cell culture process, wherein biomimetic microsystem is used as a platform.
These devices are built on silicone, which can be used to grow internal organs. This finds application in organ transplantation and also therapeutics. Harvard’s Wyss Institute is engaged in lung-on-chip production, commercialization of which would help in exponential growth of the organ-on-a-chip market. Moreover, partnerships of biotech and pharmaceutical companies with universities is expected to scale up the commercialization process in the near future. This billion dollar industry is expected to create significant market opportunities for players. Some companies such as Mimetas are currently engaged in development of kidney-on-a-chip. This technology is gaining traction as this unique technology greatly reduces the amount of testing carried out on animals, while providing highly accurate results.
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Organ-on-a-chip Market Dynamics
Organ-on-a-chip is expected to cater to wide range of applications ranging from disease modelling to patient stratification and phenotypic screening. Most of the demand is expected to be generated from lung-based organ culture, followed by kidney application. The technology offers better clinical examinations compared to petri dishes and animal testing – helping scientists and companies to better understand the functioning of internal organs such as the brain and lungs.
Funding and government initiatives are projected to further boost market growth in the near future. Though the market is expected to create substantial opportunities, high cost and early stage in R&D are some of the factors leading to slow growth of the market. Market is expected to witness rampant commercialization post-2020.
Organ-on-a-chip Market - Regional Analysis
North America and Europe are expected to dominate the overall organ-on-a-chip market throughout the forecast period. The regions are early adopters of newly developed technology. Moreover, demand is expected to be further propelled by large consumer base in these regions. North America spends over 16% of its GDP on healthcare. Moreover, various research activities are carried out in the region, which is home to some of the leading players in the market. Also, organ transplant rate is high in the region. Growth of the Europe market is expected to be primarily driven by rising demand for organ-on-chip in Germany, U.K., and France.
Asia Pacific is a lucrative market for companies engaged in organ-on-a-chip industry. However, commercialization is not expected to take place in early years. As market is still in its early stage, it would take a few years before companies can expect return on profit. Japan and China are key markets in Asia Pacific. These countries account for over half of the pharmaceutical market in Asia Pacific. Also, these countries are well equipped with technologically advanced medical devices and research centers.

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Organ-on-a-chip Market - Competitive Landscape
Organovo, Hepregen, Hurel Corporation, Nortis, TissUse, Tara Biosystems, and AxoSim are some of the players engaged in organ-on-a-chip market. These companies are located in North America, with most being start-ups albeit with major funding and are expected to attain major commercial success in the near future.
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Elderly and Disabled Assistive Devices Market to surpass US$ 26.0 Billion by 2024

The Global Elderly and Disabled Assistive Devices Market was valued at US$ 14,109.1 million in 2015 and is projected to expand at a CAGR of 7.4% during the forecast period (2016–2024), according to a new report published by Coherent Market Insights. Rapidly aging population in Asia and Latin America is a major factor propelling demand for elderly and disabled assist devices.
Asia and Latin America are expected to witness rapid growth in population aged 65 years and above through 2030. The share of elderly population in Asia is expected to increase form 7.9% in 2015 to 12.1% in 2030, as per the report ‘An Aging World: 2015’ by the U.S. Census Bureau. Also, increasing prevalence of chronic and acute diseases adds to the growing demand for technologically-advanced assistive devices for elderly and disabled population. Assistive devices such as wheelchairs, mobility scooters, walkers and rollators, and hearing and vision aids reduces dependence on others to carry out daily activities and improves quality of life of elderly and disabled patients.

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The World Health Organization (WHO) has prepared a comprehensive global disability action plan for 2014 – 2021. As per this plan, WHO intends to improve access to health services and programs, extend rehabilitation, assistive technology, assistance and support services, and support research on disability and related services. Assistive device manufacturers in the elderly and disabled assist devices market, especially in emerging economies are expected to benefit considerably through this plan.
Manufacturers in the elderly and disabled assist devices market are reaching out directly to consumers to increase their sales. Sonova Holding AG follows vertically-integrated business, wherein it also markets products through its retail stores, thus reaching out to customers and offering them customized solutions. The company acquired AudioNova in September 2016—a Netherlands-based hearing aid manufacturer—with an aim to double its presence in Europe in terms of retail stores.
Melvin ApS launched a robot called Melvin, which aids elderly and disabled people in the toilet. The robot was launched at the RoboBusiness Europe 2016 exhibition. Similarly, Vital Connect, Inc.is developing wearable health sensors that can detect body temperature, heart rate, detect falls and other such incidents in elderly and disabled patients. Such technological developments to increase individual independence and convenience is projected to lead to manifold growth of elderly and disabled assistive devices market in the near future.

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Key takeaways of the market:

• The global elderly and disabled assist devices market is expected to expand at a CAGR of 7.4% during the forecast period. Increasing demand for elderly and disabled assist devices is mainly attributed to the factors such as convenience provided by automotive assistive devices to the growing elderly and disabled population
  
• Demand for vision and reading aids is analyzed to increase rapidly during the forecast period, owing to increasing incidence of vision impairment among the geriatric populace
  
• Hearing aids segment dominates the global elderly and disabled assist devices market (in terms of revenue) and is expected to reach US$ 7,083.5 million by 2017 end. Increasing market penetration, growing average discretionary income, and improved access to hearing aids is driving revenue growth of this segment. Furthermore, baby boomers population is expected to drive growth for hearing aids over the following decade, according to William Demant Holding Group.
  
• North America dominated the global elderly and disabled assist devices market in 2015. However, the market for elderly and disabled assistive devices in Asia Pacific is projected to expand significantly at a CAGR of 8.7% during the forecast period (2016–2024)
  

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• Intense competition is witnessed among the leading players including Sunrise Medical LLC, GN ReSound Group, Sonova Holding AG, Starkey Hearing Technologies, and William Demant Holding A/S.
  

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Animal Depression Medication Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016 – 2024

Animal Depression Medication Market Overview:

Emotions may be described as subjective, conscious experiences characterized by psychophysiological expressions, mental states, and biological reactions. Several tests such as cognitive bias test and leaned helplessness models have been developed to understand feelings of optimism and pessimism in animals. Cognitive biases have been shown in wide range of species, including rats, dogs, cats, sheep, and chicks.

Depression in animals can be due to change in routine or change in emotions. Some animals can get depressed when left alone for long hours. Animals can also suffer from depression due to chemical imbalance, which can be treated with medication. Different animals have different reactions to depression. This can be spotted by looking out for ordinary behavior i.e. when an active animal becomes listless and a calm animal seems anxious. Animals in the zoo are subjected to live in artificial, stressful, and boring conditions. Detached from their natural habitats and social structures, they are kept in small, restrictive environments that deprive them of mental and physical stimulation and in turn causes depression.

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Treatment alternatives for animal depression to boost growth of the animal depression medication market

Treatment of animal depression varies according to cause of condition. Blood tests, x-rays, and a physical examination by a veterinarian can help with diagnosis. If the animal has chemical imbalance, then the veterinarian may prescribe anti-depressants or anxiety medication.

Paroxetine is an antidepressant used to treat major depressive disorders, social anxiety disorder, and panic disorder. The current standard of treatment of depression involves use of selective serotonin reuptake inhibitors (SSRIs). Depression can be triggered due to lack of serotonin, and SSRIs essentially

maintain higher levels of serotonin in the brain to address the issue. It can take up to two months for a drug to be effective in treating depression. Most dogs suffering from such disorders can make a full recovery in six to twelve months after being administered SSRIs. The U.S. Food and Drug Administration has approved only one antidepressant, Clomicalm (clomipramine) for treatment of anxiety in dogs, which would fuel growth of the animal depression medication market.

Increasing pet adoption and growing pet humanization trend driving growth of animal depression medication market in Asia Pacific and Latin America

North America is a major region for animal depression medication market. As per 2015 Pet Secure estimates, the U.S. accounted for the highest dog population of 69,929,000. Animal depression medication market in Asia is growing on account of increasing awareness among the populace regarding animal illness, increasing number of pets, and improving veterinary medical facilities. According to the Pet Asia Fair in 2016, pet adoption in Asia Pacific and Latin America regions is increasing rapidly resulting in increase in demand for nutritional and medicinal products in order to address their growing health concerns.

Increasing spending on animal care to boost growth of the animal depression medication market

Increasing number of pet animals is a major factor fueling growth of the animal depression medication market. According to 2016 estimates released by Pet Secure, over half of the population in the U.S. owns a cat or a dog. This is mainly attributed to increasing consumer awareness regarding the various social, emotional, and physical benefits associated with pet ownership. Therefore, with increasing number of pets, there is an increasing spending on pet animals, further fueled by pet humanization trend. According to 2016 estimates of Pet Secure, the U.S. population spends over US$ 50 billion per annum on their pets. This is projected to fuel growth of the animal depression medications market in the near future. Other factors include awareness about animal illness, better medical facilities, use of latest technology in diagnosis, and increased spending capabilities on animal treatment.

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Key players involved in the animal depression medication market

Major players in the global animal depression medication market include Torrent Pharmaceuticals Limited, Elite Pharma Private Limited, Biomax Laboratories, Intas Pharmaceuticals Limited, Cipla Limited, and Eli Lilly and Company. These companies provide drugs that are used to treat depression in animals.

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Laboratory Information Management Systems Market to surpass US$ 2.2 Billion by 2024Laboratory Information Management Systems Market, Laboratory Information Management Systems Market size, LIMS Market analysis, LIMS Market Trends

The Global Laboratory Information Management Systems Market (LIMS) was estimated at US$ 1,209.6 million in 2015 and is projected to reach US$ 2,271.5 million by 2024, according to a new report published by Coherent Market Insights. Increase in automation of processes in healthcare organizations is driving demand for LIMS worldwide.

Healthcare organizations are increasing spending on IT systems due to a shift towards utilization and maintenance of electronic health records (EHR). Usage of analytics techniques and big data is increasing among healthcare providers in order to improve their process outcomes and in turn make effective therapeutic decisions. Increasing trend of automating processes is pushing demand for customized solutions with multi-modality functions.

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LIMS vendors are targeting different healthcare providers such as diagnostic laboratories, private clinics, blood banks, and other such institutes where use of LIMS is becoming a necessity for providing cost-effective services to their customers.

Developed economies such as the U.S. and Western European countries are witnessing growing demand for technologically-advanced products, which can automate the healthcare process. Patients are becoming tech savvy and are using wearable devices connected with mobile healthcare applications in order to self-monitor their health. This has encouraged healthcare organizations and practitioners to transform their conventional operations by integrating the processes and patient’s critical data.

LIMS is further expected to develop with the formation of a structured regulatory framework for healthcare IT, mainly in developed economies such as the U.S., Canada, and certain Western European nations. This would facilitate exchange of information between the clinicians and patients in a secured manner.

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Key takeaways of the market:

• Demand for integrated systems is growing, with hospitals and clinical laboratories expanding their footprint by launching franchise chains. The integrated systems segment is projected to witness revenue growth at a CAGR of 7.2% during 2016 – 2024.
• Cloud-based systems provide a very cost-effective alternative to conventional systems used by healthcare providers. Market for cloud-based LIMS is expected to reach 339.8 million by 2024. Barriers with respect to security and compliance are gradually coming down leading to a growing demand for cloud-based scalable LIMS systems.
• As data analytics and big data are marking its way in the healthcare arena, the LIMS service segment is projected to expand at a CAGR of 8% during the forecast period. Data security and monitoring, customer relationship management, and patient engagement are services witnessing increasing traction from healthcare providers.
• Hospitals account for the largest market share of 49% (in terms of revenue) among end user segments in the market in 2015. The hospitals segment is expected to grow rapidly over the forecast period. Increasing patient database, organizational processes, and tests are propelling adoption of LIMS in hospitals.
• Developed countries such as the U.S. and various Western European countries are the foremost adopters of this solution in order to reduce analytical work and improve efficiency. Due to this, North America held a lion’s share of 56.4% (in terms of revenue) in 2015 in the global LIMS market. However, increasing number of healthcare facilities and rising expenditure on healthcare IT in emerging economies is anticipated to fuel demand for LIMS in these countries over the following decade.

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Market leader such as Cerner Corporation, Merge Healthcare, Inc. (International Business Machines (IBM) Corp.), McKesson Corporation, LabWare, Roper Technologies Inc., and Meditech (Medical Information Technology, Inc.) are focusing on improving services and integrating new technologies in the current LIMS systems in order to enhance the efficiency of the systems, which in turn would help healthcare providers to offer better customer experience to payers.

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Gynecological Devices Market to Surpass US$ 4.5 Billion by 2024

The Gynecological Devices Market was valued at US$ 2,667.8 million in 2015 and is projected to expand at a CAGR of 6.3% during the forecast period (2016–2024),as highlighted in a new report published by Coherent Market Insights.Increasing incidence of gynecological disorders is projected to favor the growth for gynecological devices market in the near future.
Around 10% of the global female population is affected by endometriosis according to the estimates by Endmoetriosis UK (2016). Risk of gynecological disorders increases with age. According to the World Bank, female population aged 65 years and above increased exponentially from 6.8% in 2010 to 8.2% in 2015. Furthermore, changing lifestyle habits and risk of infection is expected to result in high incidence of gynecological disorders. The outlook for the gynecological devices market is therefore bright in the foreseeable future.
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Safety is one of the major concerns of healthcare practitioners using gynecological devices. Bayer’s Essure is an intra-uterine device (IUD) that has been linked with skin rashes and pelvic pain in women (in the U.S.) who have inserted it as a permanent contraceptive solution. This has led women to remove the Essure through surgery. The U.S. FDA has called for a black box warning for the device. Furthermore, the FDA has also asked manufacturers of power morcellators to mention a warning that the product ‘has not been proved to reduce the risk of spreading cancer’. Power morcellators are used to dissect and remove uterus or uterine fibroids through small incisions. However, these devices are reported to cause uterine cancer, which remain undetected owing to lack of awareness.
Post-surgical complications are among the most frequent complications in abdominopelvic surgery. Endometriosis and infection in pelvic region can stimulate the formation of adhesions, which may lead to discomfort, chronic pain and infertility. Actamax Surgical Materials LLC (subsidiary of DSM Biomedical), submitted an Investigational Device Exemption (IDE) to the U.S. FDA in February 2017 for its Actamax adhesion barrier to be utilized in in gynecological laparoscopic surgery. Such innovative solutions for the existing concerns on the gynecological surgeries would favor the growth of gynecological devices market globally.
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Being a very intimate category of devices, safety is therefore the priority for users. Manufacturers need to gather enough evidences of safety and efficacy to avoid post-marketing recalls and regulatory hurdles. Specialized speculums, curettes, and forceps ease the surgical procedures. Demand for gynecological chairs is expected to grow rapidly during the forecast period as hospitals upgrade their infrastructure, especially in emerging economies such as India, China, and Brazil.
Key takeaways of the market:

• The global gynecological devices market is expected to expand at a CAGR of 6.3% during the forecast period (2016–2024). Rise in number of gynecological surgeries is expected to favor the growth of gynecological devices market in the near future.
  
• Surgical devices is expected to dominate the market throughout the forecast period as these devices are in regular demand for gynecological surgeries
  
• Demand for gynecological chairs is projected to grow gradually with growing investment in infrastructure upgradation and establishment of new surgical and gynecological examination rooms
  
• Gynecological devices market in the Asia Pacific region would be growing rapidly with increasing incidence of gynecological disorders and the number of gynecological surgeries
  
• Hospital are the major users of gynecological devices and would be driving the global gynecological devices market
  
• Major market payers including Ethicon, Inc., Hologic, Inc., Stryker Corporation, Cooper Surgical, Inc., Karl Storz GmbH& Co. KG, Boston Scientific Corporation, and Richard Wolf GmbH need to consider the safety of deices to avoid any post-marketing issues
  
• These players can opt for emerging nations for a rapid growth in business expansion
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Nuclear Medicine/Radiopharmaceuticals Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016-2024

Nuclear Medicine/Radiopharmaceuticals Market Overview:
Radiopharmaceuticals are unique medicinal formulations that contain radioisotopes and are used in clinical applications for diagnosis and therapy. The facilities and procedures for production, use, and storage of radiopharmaceuticals are subject to license approval either by national or regional authorities such as Nuclear Regulatory Commission (NRC) of U.S, Atomic Energy Commission (AEC) of U.S., or Atomic Energy Regulatory Board (AERB) of India. Licensing includes compliance regarding pharmaceutical preparations and use of radioactive materials.
A radiopharmaceutical preparation is a medicinal product in a ready-to-use format containing a radionuclide suitable for human use. A kit for radiopharmaceutical preparation encloses a vial containing the non-radionuclide components of a radiopharmaceutical preparation in a sterilized and validated form, to which the appropriate radionuclide is added. Radiopharmaceuticals derived from the kits are intended to be used within 12 hours of preparation.
Technetium-99m – Widely used Radioisotope in Diagnostic Procedures fueling growth of the radiopharmaceuticals market
There are over 40 radioisotopes available for use in different therapies. Technetium-99m is the most widely used radioisotope in the diagnostic procedures. Technetium-99m is used as a radioactive tracer, and can be detected in the body by medical equipment (gamma cameras). It is well suited to the role, as it emits readily detectable gamma rays with photon energy of 140 keV. According to International Atomic Energy Agency, over 80% of the total nuclear diagnostic procedures performed worldwide use Technetium-99 as a radiotracer each year and hence, propels the radiopharmaceuticals market growth.
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Radiopharmaceuticals use in Diagnostic and Therapeutic Application fuels growth of the nuclear medicine market

The chemical and physical identity is of vital importance, as during administration it targets certain tissues, binding sites, and biochemical pathways. The market is divided into two major areas, namely, diagnostic and therapeutic. Therapeutic applications of radiopharmaceuticals market include cardiology (myocardial perfusion), oncology (tumor imaging and localization), and neurology (cerebral perfusion). Radiopharmaceuticals such as iodine-131 or iodine-125 labeled m-iodobenzyl guanidine (MIGB) are used to treat pheochromocytoma and neuroblastoma. The therapeutic segment nuclear medicine market can be further sub-segmented on the basis of procedure into beta emitters, alpha emitters, and brachytherapy.
The diagnostic segment of radiopharmaceuticals market is classified into SPECT and PET. Single photon emission computed tomography (SPECT) adoption has grown steadily over the last decade and is used in the study of cerebral blood flow imaging. Positron emission tomography (PET) is a functional imaging technique used to observe metabolic processes in the body. System detects pairs of gamma rays emitted by a positron emitting radionuclide. SPECT radioisotopes are used for diagnosis of diseases such as cancer, cardiovascular diseases, and thyroid and neurological disorders.
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Radiopharmaceuticals – Used in Hospitals for Diagnosis
End users of radiopharmaceuticals include hospitals, research institutes, and diagnostic labs. These can be used in hospitals for diagnosis and detection of various diseases such as bone-related pathology, bone pain, stress fracture, bone infections, and spread of cancer in the bone. They are also used in detection and scanning such as in neurology and cardiology.
Application of Radiopharmaceuticals across the Globe
Radiopharmaceuticals are widely used in North America, mainly due to availability of advanced healthcare infrastructure, technological advancements, superior medical facilities, and supportive government support. These are also widely used in Europe due to new procedures for diagnosis of diseases and robust medical infrastructure in the region. Radiopharmaceuticals market is projected to witness rampant growth in Asia due to rapid rise in research work in the sector and rising public awareness.
Key players involved in Nuclear Medicine market
The market is fragmented, with the presence of various major players such as Kimberly-Clark Corporation, Eli Lilly and Company, Lantheus Medical Imaging Inc., Ampio Pharmaceuticals Inc., GE Healthcare, Piramal Imaging, Covidien Plc., Cardinal Health, Iso Tex Diagnostics, Inc., Jubilant DraxImage Inc., Bayer HealthCare Pharmaceuticals Inc., Bracco Diagnostic Inc., Navidea Biopharmaceuticals, Nordion Inc., Spectrum Pharmaceuticals, Inc., Mallinckrodt Plc., Bio-Nucleonics Inc., and IBA-Molecular.
Conclusion
Growth of the radiopharmaceuticals market is projected to witness rapid traction in the near future due to its high potential in diagnosis and detection of diseases related to cardiology, neurology, and oncology. Developed regions are expected to be highly lucrative markets for this technology, due to the high capital investment involved and availability of advanced medical facilities in these regions. Major players in the global Positron Emission Tomography (PET) scanners market are concentrating on enhancing their global and regional presence through strategic operational expansion and collaborations with regional players.
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Pharmacy Benefit Management Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast to 2024

Pharmaceutical drug prices continue soaring up and contribute significantly to total healthcare expenditure worldwide. The cost of drugs has risen more than any of the healthcare expenditure. As per the insurance consultants at Milliman, drug costs were merely 16% of the overall health costs in 2015, which rose by 102% over a decade and accounted for around 14% in 2015. Rising drug prices and increasing consumer spending on prescription drugs drives demand for pharmacy benefit managers (PBMs). The pharmacy benefit management system is operated by third party administrators (TPAs) who act as a liaison between pharmacists, insurance providers (payers), and drug manufacturers. There are established companies offering these services who aid in reducing drug prices by negotiating with retail pharmacies and drug manufacturers. Patients who have enrolled in various health plans and those uninsured can get the benefits of pharmacy benefit management system. Health plans collaborate with the pharmacy benefit managers to offer medications at a lower price than those available at retail pharmacies.

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Moreover, PBMs also aid in planning and managing the formulary as per customer needs, negotiating discounts and rebates with drug manufacturers, contracting with pharmacies, and processing the prescription claims. To manage the cost of prescription drugs and improve the customer value, PBMs use various tools such as pharmacy networks, mail-service pharmacies, drug formulary, e-prescribing, manufacturer’s discount, disease management, drug utilization review, and pharmacy discount cards (for the uninsured). To manage these tools and the PBMs account, there are various prescription claim software/systems marketed worldwide.

Pharmacy Benefit Management Market Taxonomy

The global pharmacy benefit management market can be analyzed on the basis of the beneficiaries of these services i.e. the healthcare providers, employers, and drug manufacturers. A major population in the U.S. receives healthcare benefits from their employers. Therefore, employers are also seeking to reduce their costs and opt for pharmacy benefit management services. The providers of pharmacy benefit management services also manage the prescription drug claims i.e. act as a link between the payers and health insurers.

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The Pharmacy Benefit Management Market is Highly Concentrated in Developed Markets

The global market in pharmacy benefit management is analyzed across five major regions - North America, Europe, Asia Pacific, Latin America, Middle East, and Africa. Presence of PBM is concentrated in the developed economies of North America and Europe. Increase in subscribers of Medicare prescription drug program is projected to fuel demand for PBMs in the U.S. Besides, the pharmacy benefit managers also aid in deciding whether a generic or branded product would benefit the patient. Patents for around 40 blockbuster brands worth US$ 155 billion are expected to expire by 2020. Generics have a good profit margin, which can benefit the pharmacy benefit managers/management companies, thus favorably shaping the pharmacy benefit management market outlook. Similar scenario is observed in the Europe pharmacy benefit management industry.

Challenges faced in the Pharmacy Benefit Management Market

With the introduction of expensive treatments/drugs for chronic diseases such as cancer, and hepatitis, demand for PBMs is projected to increase significantly. However, even with the presence of major players in this industry, the PBMs have been ineffective in curbing the drug price hike. Further, with the advent of Affordable Care Act and the constant endeavor of governments to reduce and cap the drug prices, profitability of this industry is expected to be significantly impacted in the near future.

Some of the major players present in the global pharmacy benefit management market include Express Scripts, CVS Caremark, Prime Therapeutics, United Health / OptumRx, Catamaran Corporation, Humana Pharmacy Solutions and MedImpact. Express Scripts acquired Medco Health Solutions for US$ 29.1 billion in April 2012, making it a leader with a significant share in the global pharmacy benefit management industry. With increasing competition, industry consolidation is expected to be a prevalent trend in the near future.

Key players engaged in the elbow lesion market

The PBMs have been ineffective in curbing the drug price hike. Further, with the advent of Affordable Care Act and the constant endeavor of governments to reduce and cap the drug prices, profitability of this industry is expected to be significantly impacted in the near future.

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Malaria Vaccines Market to Surge past US$ 591.8 Million by 2024

The Global Malaria Vaccines Market is pegged to be valued at US$ 8.5 million in 2018 and is projected to expand at a CAGR of 102.8% during the forecast period (2018-2024), as highlighted in a new report published by Coherent Market Insights.Rise in demand for vaccines for important indications on the backdrop of increasing focus on biological preparations is expected to be a major factor driving growth of the global malaria vaccines market over the foreseeable future.

According to World Health Organization (WHO) malaria fact sheet and World Bank estimates, over 40% of the global population is at risk of malaria. World Health Organization (WHO), there were around 214 million malaria cases reported in 2015, leading to 438,000 deaths worldwide. Over 70% of these deaths were among children under 5 years of age. Sub-Saharan Africa accounts for the highest share of global malaria burden, with around 89% of malaria cases and 91% of malarial deaths in 2015. Such high impact of this life-threatening disease is influencing governments across various countries, companies, investors, and non-profit organizations to contribute towards curbing spreading of this disease. Since the problem of malaria is burdening many of the emerging and under developed regions such as in Africa and Asia Pacific, various initiatives have been implemented in these regions to drive down high costs of the vaccine in development. For instance, in 2016, GSK announced plans to develop vaccines at a mere profit margin of 5% of the cost of the vaccine. Governments across most regions are actively involved in programs aimed at eliminating malaria. For instance, WHO had mobilized funding for pilot program in first phase between 2017 and 2020 by the global fund to fight against malaria and other disease such as AIDS and tuberculosis prevalent worldwide.

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Shift from pharmaceutical oral dosage forms to parenteral dosage forms is expected boost the malaria vaccines market globally. The emerging economies are undergoing a wave of various healthcare reforms. Healthcare treatment regimens are becoming more reliable for the growth of the global market, with various initiatives in place to eradicate the menace of malaria. In 2016, in India, the National Framework for Malaria Elimination (NFME), was launched to eliminate the problem in the country. This program was based on the Framework by the National Vector Borne Disease Control Program (NVBDCP) of the Ministry of Health and Family Welfare. According to NFME, in 2012, the total economic burden of malaria in India was around US$ 1,940 Mn, with 75% from lost earnings and 25% from treatment costs borne by households.

According to World Malaria Report 2015, India accounts for around 70% of the total malaria incidence rate in the South-East Asia. In 2014, the incidence rate of malaria in the country was around 0.89 per 1,000 person at risk per year. Around 1.1 Mn cases were reported, which lead to 562 deaths in India in 2014.

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Key takeaways of the malaria vaccines market:

The global malaria vaccines market is expected to expand at a CAGR of 102.8% during the forecast period (2016–2024) as there exists a large unrealized market especially in Africa, Asia Pacific, Latin America and Middle EastThe Pre-Erythrocytic Vaccine dominates the market in the vaccines type segment, as it is used to prevent the infection completely, while blood-stage vaccines aim to reduce or eliminate the parasite load once a person is infected

Plasmodium Falciparum is the major agent segment of malaria vaccines market, as Plasmodium falciparum infection are induced by the asexual stages of the parasite that develop inside red blood cells, making it one of most severe forms of malaria among various types of parasites causing malaria

Some of the major players involved in global malaria vaccines market are GlaxoSmithKline plc, Sanaria Inc, Nobelpharma Co., Ltd., Sumaya Biotech and GenVec, Inc.

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Home Healthcare Software Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016-2024

Home Healthcare Software Market overview:

Home healthcare services market is expected to grow at a robust rate between 2016 and 2024, with emergence of new entrants in market and improving macroeconomic conditions worldwide.

Until recently, medical documentation involved cumbersome paper work. Technological advancements and introduction of advanced software has eased the way industry use to operate, making work process easier and more efficient. Healthcare industry has greatly benefitted from integration of IT systems. With technological advancements, home healthcare software such as telehealth solutions and clinical management systems are available in the market.

Home healthcare enables healthcare services to be delivered at patient’s home – thereby alleviating healthcare costs.

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Population aged above 65 years forms the bulk of home healthcare software market

Home healthcare market is driven by various sociological, demographics, and macroeconomic factors, most notably the integration of information technology solutions in healthcare industry to meet challenges in patient data retrieval, payment and claim processing as well as storage and accessibility. This is further propelled by government initiatives to improve healthcare infrastructure.

High prevalence of chronic disorders among geriatric population in turn fuels demand for nursing homes and assisted living care facilities for specialized attention. However, introduction of home healthcare software solutions is expected to bridge the gap between geriatric patient expectation and healthcare providers. The system offers solutions at patient’s home, thereby minimizing overall operational cost and high ROI for providers as well.

Though the market is expected to grow at a rapid rate, weak financial support from government along with low adaptability in emerging economies are major challenges inhibiting growth of overall industry.

Home Healthcare Software Market Taxonomy:

Coherent Market Insights (CMI) has segmented the home healthcare software market by:

• Product Type
• Therapeutic Application
• Devices
• Platform
• End User

By product type, the home healthcare software market has been segmented into agency homecare software, hospice solutions, telehealth solutions, clinical management systems, and others.

On the basis of therapeutic application, CMI has segmented the home healthcare software market into clinical and non-clinical solutions. Clinical segment is expected to grow at impressive rate over the forecast period.

On the basis of devices, mobile devices are expected to gain traction over laptop and tablet in the home healthcare software market.

Homecare agencies and hospice agencies are key end-use segments in the home healthcare software market.

Alignment between payers and providers along with access to electronic health records has boosted overall North America home healthcare software market growth

Among regions, North America is expected to dominate the global home healthcare software market throughout the forecast period. However, the market in the region is expected to lose considerable

market share to developing regions, namely Latin America and Asia. Growth of the market in the region is primarily driven by increasing demand in the U.S., accounting for over 85% of overall market. Technological advancements along with high healthcare spending across all verticals is expected to propel market growth. Moreover, health awareness level among the population in developed regions is high compared to other regions. However, the market in Canada is expected to witness sluggish growth over the forecast period.

Europe is the second-largest market and is expected to create substantial opportunities for players. Over 65% of the revenue generated in the regional market is expected to be from Germany, UK and France. Markets in Russia and Poland are expected to grow at substantial rate.

Asia-Pacific is a lucrative market for home healthcare software due to the easy availability of skilled manpower, cheap labor and highly developed information technology sectors in the countries particularly China and India. Moreover, India is one of the leading markets for IT software. Relaxation in FDI cap is expected to boost overall presence of MNCs in the region. Though the Asia Pacific market is vibrant, there are a lot more challenges present in the market that inhibit proper capitalization of the market opportunities. The market is highly volatile with wide variations in demographics and economic conditions. The market in China, once the power engine of Asia Pacific, is witnessing low growth, due to noticeable decline in healthcare expenditure in the region. On a positive note, India is witnessing rapid transformation across various healthcare verticals. Companies need to fully understand the demographic and macroeconomic situation to generate high ROI from the region. Markets in Latin America and MEA are expected to witness sluggish growth over the forecast period.

Some of the major companies contributing to the global home healthcare software market are Agfa Healthcare, Mckesson Corporation, NextGen Healthcare Information System LLC, GE Healthcare, MEDITECH, Medical Information Technology, Inc. (Meditech), Cerner Corporation, Siemens Healthcare and Allscripts Healthcare Solutions, Inc.

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Pressure Bandages Market Size, Share and Forecast upto 2024

Pressure Bandages Market Overview:
Leg ulcer is one of the most common ailments among the adult population. It is a fault in the skin of the lower portion of the leg with slow or no healing propensity of a wound over a period of 3 months. Simply put, a leg ulcer is a rupture in the leg skin, which permits bacteria and air to permeate into the fundamental or underlying tissue. Leg ulcers are usually caused by injury that breaks the skin.
The management of chronic leg ulceration include a variety of compression therapies such as garments such as bandages and stockings and intermittent pneumatic. Pressure bandages falls under the category of compression garment that aids in faster healing and controlling infection of wounds, while prevention of excessive blood loss as well. Compression bandages also called pressure bandages, are a kind of field dressing used to apply pressure to a wound. These are usually wrapped around the wound and are then pulled tight to maximize the pressure applied in the area. Pressure bandages are usually used in situations where instantaneous first aid is necessary to protect one’s health. They are wrapped around the lower limb to apply a desired pressure that offers a degree of firmness directly to the wound. Pressure bandages are predominantly used for treating venous leg ulcers, swelling, oedema, sprains, and other lymphatic conditions.
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One of the important factors is to apply the pressure bandage carefully or else it can lead to a several complications such as tourniquet negative effect and decrease blood pressure. The primary symptoms of leg ulcer are friable granulation, cramps in the calves, skin discolorations and dermatitis. Around 2 to 3 million people in the U.S. are identified with chronic wounds each year, according to the Wound Healing Society (a scientific group focused on wound healing). The rising prevalence of chronic leg ulcer will lead to an increase in demand for pressure bandages during the forecast period.
Pressure Bandages market Taxonomy
On the basis of product type, the global market is classified into:

• Long Stretch or Elastic Bandages
  
• Multi-component Multilayer Bandage Systems (MLBs)
  
• Short Stretch or Low-elasticity Bandages
  

On the basis of raw material, the global market is classified into:

• Cotton Fabric
  
• Latex
  
• Polymer
  
• Fiber
  

The elastic or long stretch bandages held a significant market share in the global pressure bandages market. High elasticity of over 100% and its high extensibility that can apply constant pressure to the wound directly, are some of the factors responsible for the dominance of the segment in the global pressure bandages industry. These pressure bandages are usually recommended for stationary patients who are incapable of activating their calf-muscle pump. Multi-component multilayer bandages act as an alternative to long elastic pressure bandages. They deliver constant and consistent compression for managing lower leg ulcers.
Growing prevalence of chronic leg ulcer and increase in the geriatric population will drive the overall pressure bandages market
An independent study available in Hindawi Publishing Corporation (a commercial publisher of technical, scientific, and medical literature) revealed that 1% of the overall adult population suffers from chronic leg ulceration and it affects 3.5% of people older than 65 years. North America accounted for the maximum share in the global pressure bandages market, followed by Asia Pacific. This is mainly attributed to high prevalence of chronic leg ulcers, presence of large number of manufacturers of pressure bandages, developed healthcare facilities, and increase in research related activities.
The emerging economies of India and China in Asia Pacific hold enormous potential for growth of the market due to the presence of large elderly population, considerable growth in private & public hospitals and drug stores, growing per capita income coupled with growth in healthcare expenditure. This region is expected to grow at a maximum rate in the global pressure bandages market over the course of the forecast period.
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Some of the companies operating in the pressure bandages market in the current scenario are BSN medical, 3M, Johnson & Johnson, Lohmann & Rauscher, Smith & Nephew, and Covidien. Some of the other companies operating in the market are Datt Mediproducts Private Limited, Moore Medical LLC, Mölnlycke Health Care, Dynamic Techno Medicals and Paul Hartmann Pty. Ltd.
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Bone Growth Stimulator Market Size, Share and Forecast upto 2024

Bone Growth Stimulator Market Overview:
Bone growth stimulators or BGSs are supplemental devices that are worn after a lumbar (low back) or cervical (neck) spine surgery. Bone growth stimulators can be used to assist spinal bone fuse after a failed fusion procedure. Bone growth stimulation for the cervical and lumbar spine has significant benefits after a fusion procedure. Various doctors recommend BGS for post-operative lumbar and cervical cases. A bone growth stimulator sends low intensity electrical signals to the site of fusion. These electrical signals trigger natural bone healing process of the body, which are sometimes impaired in surgery patients. The global demographic scenario is quite diverse. For instance, India is a country with more than half of the population in the youth bracket, whereas China and the U.S. have the maximum geriatric population. Bone growth stimulators have observed an implausible demand in the past few years. The early development of BGS began in the U.S. and the innovation in technology has made developed and sophisticated products to enter the market.
According to the International Osteoporosis Foundation, osteoporosis causes around 8.9 million fractures per year that is around one osteoporotic fracture every 3 seconds. Moreover, osteoporosis is expected to affect around 200 million women worldwide. Around 80%, 75%, 70% and 58% of forearm, humerus, hip and spine fractures, respectively, affects women. A fracture, especially in the spinal cord requires bone surgery. Out of these surgeries, a significant number of patients will need bone growth stimulators due to steady recovery. This in turn will drive the growth of the overall bone growth stimulator market during the forecast period.
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Bone growth stimulator market Taxonomy
On the basis of type of product, the global bone growth stimulator market is classified into:
Pulsed Electromagnetic Field (PEMF) Devices
Capacitive Coupling (CC) Devices
Combined Magnetic Field (CMF) Devices
Ultrasound Bone Growth Stimulators Surgical Devices
Invasive Electrical Bone Growth Stimulators
On the basis of type of application, the global market is classified into:
Trauma injury and Fractures
Spinal Fusion
Osteogenesis
Some of the factors such as rise in per capita healthcare spending, increase in personal income, and improvement in healthcare sector will boost growth of the market in bone growth stimulator, globally. Nonetheless, a variety of factors such as uncertainty about efficacy, and availability of alternative therapies may hinder the growth of the overall market.
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Increasing prevalence of vertebral fractures, especially in the geriatric population will drive the overall bone growth stimulator market
According to the International Osteoporosis Foundation, the number of vertebral fractures that are not recognized is as high 45% in North America, and 46% in Latin America. After a surgery for a vertebral fracture, there is a high risk of requiring hospitalization for another fracture in the following years. To decrease the morbidity rates in patients with a history of bone surgeries, bone growth stimulators are used extensively. As the number of cases is increasing at an alarming rate, so is the need for bone growth stimulators. This will encourage the growth of the global bone growth stimulator market in the forecast period.
As per the International Osteoporosis Foundation, white women aged 50 years are at 16% lifetime risk of occurrence of a vertebral fracture, whereas the percentage is 5 for white men. The staggering percentage of the population with risk of vertebral fracture above the age of 50 will be responsible for increased number of bone surgeries, thereby augmenting the growth of bone growth stimulators. By geography, North America is likely to dominate the bone growth stimulator industry owing to various factors such as consumer awareness about treatments related bone fracture and injury and high healthcare expenditure. Western Europe will follow North America in terms of market share. Availability of advanced public health systems and subsidies, along with high adoption of new technologies such bone growth stimulators in this region are some of the factors for this region’s high market share.
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Some of the companies operating in the bone growth stimulator market in the current scenario are Orthofix International N.V., Aetna Inc., DJO LLC, Smith & Nephew, Zimmer Biomet Holdings Inc., Ossatec Benelux BV, Elizur, Bioventus LLC., Orchid Medical, IGEA S.p.A, and Verve Consulting Inc.
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